1) Hyperpigmentation removal with a lower “collateral heat” profile
The pulse duration of pico lasers is so short, the dominant effect from this laser is photoacoustic / photomechanical fragmentation of pigment rather than prolonged heating. This is one reason pico lasers are widely used for lightenting dark spots in patients with darker skin, especially in Asia.
2) Texture + scar remodelling (with fractional pico delivery)
With fractional optics (e.g., diffractive lens array), pico lasers can create microscopic zones of injury (i.e. laser-induced optical breakdown) that stimulate dermal remodelling while keeping downtime relatively low compared with fully ablative resurfacing from other types of lasers for acne scars.
3) Evidence in melasma (with important caveats)
Studies in Asian skin show improvement in melasma severity and skin quality with fractional 1064 nm picosecond treatment, but melasma remains prone to relapses. Pico lasers work well and safely, as part of a long-term plan (sun protection, trigger control, topical maintenance).