Acne Treatments in Singapore: What Actually Works?

By Dr Rachel Ho

By Dr Rachel Ho

Acne treatment is selected according to the type of breakouts, their severity, previous treatment response and the effect on daily life1,2. Options include topical medicines, oral treatment and selected procedures, with the approach adjusted for medical history, pregnancy plans and skin tolerance1,2.

At The Skin Longevity Clinic, Dr Rachel Ho begins by assessing the acne pattern and reviewing previous treatments before recommending medication or a procedure. The aim is to control new breakouts, address the risk of marks and scars, and establish care that remains manageable between appointments.

Acne treatment options at a glance

Different acne patterns call for different treatment discussions2. The table provides an overview rather than a prescription, and the final choice also depends on individual suitability1,2.

Treatment can change as the skin improves or circumstances change. A review should establish whether the current approach remains appropriate before further medicines or procedures are added.

Acne patternTreatment options that may be discussed
Blackheads and whiteheadsTopical treatment, often including a retinoid to address follicular blockage2,3.
Mild inflammatory acneTopical combinations that address blockage, bacteria and inflammation1.
More extensive inflammatory acneTopical treatment with an oral medicine where appropriate2.
Persistent acne in womenTopical treatment and, in suitable patients, hormonal options4.
Deep, scarring or difficult to control acneAssessment for isotretinoin or other escalation of treatment1.
Flat marks or indented scarsSeparate assessment of the residual colour or structural change, alongside control of active acne2.

When should you see a doctor for acne?

Painful or persistent breakouts, developing scars and an inadequate response to previous treatment are reasons to seek medical assessment1. The effect on confidence and daily life also deserves attention, even when the number of visible spots seems small1.

Acne severity involves more than counting pimples2. The depth of the lesions, areas affected, scarring and personal impact all contribute to treatment decisions2. PubMed

What happens during an acne consultation?

Dr Rachel Ho examines the types of lesions present, including blackheads, whiteheads, inflamed spots and deeper nodules. The assessment also considers their distribution, skin sensitivity, existing pigmentation and scarring.

Previous treatment is an important part of the discussion. Bring the names of products or medicines you have used, approximately how long you used them, and any improvement or irritation you noticed.

The consultation also covers relevant medicines, supplements, menstrual patterns and pregnancy plans. These details help explain previous responses and identify considerations that may affect the next treatment choice.

Our guide to your first clinic consultation explains how to prepare. Ask what the proposed treatment is intended to achieve, what its limitations are and how progress will be reviewed.

How are acne medicines selected?

Topical medicines

Topical retinoids help reduce follicular blockage and treat comedones, while benzoyl peroxide provides antimicrobial activity against acne associated bacteria2. Azelaic acid is another option, including when acne occurs alongside brown marks3. PubMed

Dryness and irritation can affect how comfortably these treatments are used3. The formulation and application schedule can be adjusted, with suitable moisturiser and gentle cleansing supporting tolerance3. PubMed Central (PMC)

For an explanation of the different treatment approaches, read Dr Rachel Ho’s guide to acne causes and treatment evidence. Use it alongside your consultation to clarify the purpose of each part of the proposed regimen.

Oral antibiotics may be considered for inflammatory acne that requires more than topical treatment1. They should be combined with appropriate topical therapy, including benzoyl peroxide, and their duration limited to reduce antibiotic resistance1.

An antibiotic course should have a review point rather than continue indefinitely1. Ongoing acne control needs to be considered when the course ends3.

Spironolactone and selected combined oral contraceptives are options for suitable women with persistent acne4. The choice requires consideration of pregnancy plans, medical history, other medicines and treatment preferences4.

The detailed relationship between hormones, blood tests and recurring breakouts is covered in Dr Rachel Ho’s adult female acne article. Mention any menstrual changes or recurring patterns during your consultation so these can be considered in the assessment.

Isotretinoin may be considered for severe acne, acne causing scarring or substantial distress, and acne that has responded inadequately to other treatments1. Treatment requires discussion of adverse effects and monitoring, including dryness and relevant blood tests3.

Pregnancy prevention is essential because isotretinoin is contraindicated during pregnancy5. Your doctor should explain the precautions and review arrangements before treatment begins5.

Where do acne procedures fit?

Procedures should be considered for a defined concern, with the evidence and limitations explained alongside medical options. A discussion should distinguish treating active acne from addressing the marks or scars left behind.

Chemical peels

A systematic review of 12 randomised trials found that chemical peels may improve acne, although study quality ranged from very low to moderate6. The evidence was insufficient to identify one peel as consistently superior6.

Our chemical peel guide explains this treatment category. Ask which concern the proposed peel addresses and how it fits with your current skincare and medication.

LED light treatment

Studies of blue light treatment have produced mixed findings, with limitations including small samples, short follow up and risk of bias7. A systematic review advised caution when interpreting the available evidence7

The clinic’s LED light treatment guide provides further background. Discuss the expected contribution of light treatment before deciding whether to add it to a medical regimen.

Selective sebaceous gland radiofrequency

Selective sebaceous gland radiofrequency has been studied for inflammatory acne8. In a randomised study with 63 participants completing treatment, the treated group showed greater improvement in inflammatory lesions at 12 weeks than the control group8.

Our guide to selective sebaceous gland treatment explains the approach. Any recommendation should identify the lesions being targeted and the role of ongoing acne care.

How long does acne treatment take?

Many acne treatments need six to eight weeks before improvement becomes noticeable9. An initial treatment review at around 12 weeks is commonly recommended, although the appropriate timing depends on the treatment and clinical circumstances9.

The review should consider new breakouts, discomfort, irritation and how consistently the regimen has been manageable9. The purpose is to decide whether to continue, simplify or adjust treatment rather than judge progress from a single spot.

Contact the clinic earlier when treatment causes troublesome symptoms or the acne is worsening. Bring details of what has changed, including any products added since the previous appointment.

What happens when acne returns?

Acne can recur after treatment, including after a course of isotretinoin10. A large cohort study published in 2025 documented patients requiring further acne treatment after completing isotretinoin, illustrating that initial improvement and lasting remission are different outcomes10.

Maintenance treatment may help preserve improvement, with topical retinoids recommended for suitable patients after successful acne control3. The plan should explain what to continue, what can be reduced and when reassessment is appropriate3.

A return of breakouts is a reason to review the pattern and previous response. Discuss the timing, severity and any difficulty continuing the earlier routine before deciding on another course or additional procedure.

What skincare supports acne treatment?

Gentle cleansing and a suitable moisturiser can help reduce irritation associated with topical acne medicines3. Avoiding harsh cleansers and unnecessary astringents is also part of improving treatment tolerance3.

Keep a record of the products you use so the routine can be reviewed as a whole. Dr Rachel Ho’s guide to skincare ingredients for acne can help you prepare questions about ingredients already in your bathroom cabinet.

What about back and body acne?

Acne can affect the chest and back as well as the face2. The extent of involvement helps determine whether topical treatment is sufficient or an oral option should be discussed2.

The clinic’s back and body acne guide covers these concerns separately. Mention every affected area during assessment, even when facial breakouts are the main reason for your visit.

Can acne marks and scars be treated alongside active acne?

Flat red or brown marks differ from scars that alter skin texture2. Identifying which changes are present helps separate the goal of reducing new breakouts from treatment of existing colour or structural changes2.

The timing of additional treatment should be discussed alongside the acne plan. Some approaches can address acne and pigmentation together, while structural scar procedures require a separate assessment3.

Our guide to acne marks and acne scars explains the distinction. Readers concerned about indentations can also consult the acne scar treatment guide before discussing suitable options.

What changes during pregnancy or breastfeeding?

Pregnancy plans should be discussed before starting or continuing acne medicines5. Isotretinoin is contraindicated during pregnancy, while spironolactone and topical retinoids should also be avoided during pregnancy5. Azelaic acid and benzoyl peroxide are among the topical options that may be considered after medical review5.

Breastfeeding requires a separate assessment because the recommendations differ from those for pregnancy5. Tell the doctor about current pregnancy, breastfeeding or plans to conceive so that the treatment discussion reflects your circumstances5.

How much does acne treatment cost in Singapore?

The cost of an acne plan depends on what is recommended after assessment. Ask for the consultation fee and clarify the expected costs of medicines, any indicated tests, review appointments and optional procedures before proceeding.

It is useful to distinguish the cost of starting treatment from the cost of ongoing care. Our consultation guide explains questions to ask about estimates, inclusions and follow up. Skin Longevity Clinic

FAQs

What is the best acne treatment in Singapore?

The best treatment depends on lesion type and severity. Combination topical therapy suits many patients, oral antibiotics can help widespread inflammation, hormonal treatment can suit selected women and isotretinoin is often the strongest option for severe or scarring acne.

Is isotretinoin the best acne treatment?

Isotretinoin is the most effective systemic treatment for severe, scar forming and treatment resistant acne. Mild comedonal acne usually does not require the exposure and monitoring associated with an oral retinoid.

Are lasers or RF better than acne medication?

Medication has the strongest and most consistent evidence across common acne patterns. Laser, LED, peels and selective RF can add value for selected patients, but each addresses only part of acne biology.

Can acne be cured permanently?

Many patients achieve prolonged control, and isotretinoin can produce remission. Acne can still relapse because hormonal influences, sebum activity and genetic susceptibility continue over time.10

Do I need blood tests before acne treatment?

Blood tests are selected according to the medicine being considered and the findings at assessment. Oral isotretinoin, for example, involves lipid and liver function checks before and during treatment1,3. Your doctor should explain which tests are needed and how the results affect the plan.

Should I apply acne cream only to individual pimples?

Most topical acne medicines are applied as a thin layer across the whole acne prone area rather than dotted on visible spots, because they also work on blockages that have not yet become visible1. Follow the instructions for your prescribed product, including how much to use, how often and which areas to avoid.

Acne assessment at The Skin Longevity Clinic

Dr Rachel Ho is the founder of The Skin Longevity Clinic at 9 Scotts Road, Scotts Medical Center at Pacific Plaza, Singapore 228210. Her assessment considers the acne pattern, skin tolerance, previous response and relevant medical history before treatment is recommended. theskinlongevityclinic.com

To arrange a consultation, contact The Skin Longevity Clinic or call +65 6514 2688. Bring your current skincare and treatment details, together with the questions you would like the assessment to address. theskinlongevityclinic.com

Related reading at TheSkinLongevityClinic.com

The Skin Longevity Clinic is a doctor led practice at 9 Scotts Road, #06-05 Scotts Medical Center at Pacific Plaza, Singapore 228210, near Orchard Road. Treatment begins with assessment of acne type, severity, scarring risk, pigmentation tendency, skin barrier and previous response before medication or a procedure is recommended.

Journal references

1. Reynolds RV, Yeung H, Cheng CE, et al. Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology. 2024;90(5):1006.e1 to 1006.e30. doi:10.1016/j.jaad.2023.12.017.

2. Eichenfield DZ, Sprague J, Eichenfield LF. Management of Acne Vulgaris: A Review. JAMA. 2021;326(20):2055 to 2067. doi:10.1001/jama.2021.17633.

3. Oon HH, Wong SN, Aw DCW, Cheong WK, Goh CL, Tan HH. Acne Management Guidelines by the Dermatological Society of Singapore. Journal of Clinical and Aesthetic Dermatology. 2019;12(7):34 to 50. Full article.

4. Smith CA, Gosnell E, Karatas TB, et al. Hormonal Therapies for Acne: A Comprehensive Update for Dermatologists. Dermatology and Therapy. 2025;15(1):45 to 59. doi:10.1007/s13555-024-01324-8.

5. Ly S, Kamal K, Manjaly P, Barbieri JS, Mostaghimi A. Treatment of Acne Vulgaris During Pregnancy and Lactation: A Narrative Review. Dermatology and Therapy. 2023;13(1):115 to 130. doi:10.1007/s13555-022-00854-3.

6. Chen X, Wang S, Yang M, Li L. Chemical peels for acne vulgaris: a systematic review of randomised controlled trials. BMJ Open. 2018;8(4):e019607. doi:10.1136/bmjopen-2017-019607.

7. Scott AM, Stehlik P, Clark J, et al. Blue Light Therapy for Acne Vulgaris: A Systematic Review and Meta Analysis. Annals of Family Medicine. 2019;17(6):545 to 553. doi:10.1370/afm.2445.

8. Ahn GR, Kim JM, Park SJ, Li K, Kim BJ. Selective Sebaceous Gland Electrothermolysis Using a Single Microneedle Radiofrequency Device for Acne Patients: A Prospective Randomized Controlled Study. Lasers in Surgery and Medicine. 2020;52(5):396 to 401. doi:10.1002/lsm.23152.

9. Santer M, et al. Managing acne vulgaris: an update. Drug and Therapeutics Bulletin. 2024;62(1):6 to 10. doi:10.1136/dtb.2023.000051.

10. Lai J, Barbieri JS. Acne Relapse and Isotretinoin Retrial in Patients With Acne. JAMA Dermatology. 2025;161(4):367 to 374. doi:10.1001/jamadermatol.2024.5416.