Dr Rachel Ho on q-switch laser
Q-switched Nd:YAG 1064 nm is an established laser treatment in dermatology for pigment, tattoo ink and acne. The best outcomes come from matching the laser physics to your pigment biology: where the pigment sits, why it formed, and how your skin responds to inflammation. Evidence reviews and clinical studies consistently show that results are achievable, but complications can occur when protocols are overly aggressive, so treatment should be medically guided and combined with long-term pigment control strategies.
References
- Wang CC, et al. A comparison of Q-switched alexandrite laser and intense pulsed light for the treatment of freckles and lentigines in Asian persons: a randomized, physician-blinded, split-face comparative trial. J Am Acad Dermatol. 2006;54(5):804–10. doi:10.1016/j.jaad.2006.01.012.
- Ho SG, et al. A comparison of Q-switched and long-pulsed alexandrite laser for the treatment of freckles and lentigines in oriental patients. Lasers Surg Med. 2011;43(2):108–13. doi:10.1002/lsm.21045.
- Chen J, et al. Efficacy of low-fluence 1064 nm Q-switched Nd: YAG laser for the treatment of melasma: A meta-analysis and systematic review. J Cosmet Dermatol. 2022;21(7). doi:10.1111/jocd.15126.
- Chan NP, et al. A case series of facial depigmentation associated with low fluence Q-switched 1,064 nm Nd:YAG laser for skin rejuvenation and melasma. Lasers Surg Med. 2010;42(8):712–9. doi:10.1002/lsm.20956.
- Kwon HH, et al. Combined treatment of melasma involving low-fluence Q-switched Nd:YAG laser and fractional microneedling radiofrequency. J Dermatolog Treat. 2019;30(4):352–356. doi:10.1080/09546634.2018.1516858.
- Ungaksornpairote C, Manuskiatti W, Junsuwan N, Wanitphakdeedecha R. A prospective, split-face, randomized study comparing picosecond to Q-switched Nd:YAG laser for treatment of epidermal and dermal pigmented lesions in Asians. Dermatol Surg. 2020;46(12):1671–5. doi:10.1097/DSS.0000000000002486. PMID 32604235.
- Kim JY, Yang J, Huh G, Choi YJ, Kim WS. A split-face, single-blinded, randomized controlled comparison of 532 nm picosecond Nd:YAG laser versus 532 nm Q-switched Nd:YAG laser in the treatment of solar lentigines. Ann Dermatol. 2020;32(1):8–13. doi:10.5021/ad.2020.32.1.8. PMID 33911703.

